Gene description for ESYT2
Gene name extended synaptotagmin 2
Gene symbol ESYT2
Other names/aliases CHR2SYT
E-Syt2
FAM62B
Species Homo sapiens
 Experiment description of studies that identified ESYT2 in Melanoma cells

1
Experiment ID496
Identified moleculemRNA
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Microarray
PubMed ID 23344721   
OrganismHomo sapiens
Experiment descriptionmiR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
AuthorsBolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O.
Journal name Mol Ther Nucleic Acids
Publication year2012
SampleMelanoma cells
Sample namePrimary malignant melanoma cells (0105)
Isolation/purification methods-
Flotation density-
Molecules identified in the studymRNA
Methods used in the studyMicroarray
EV-TRACK -

2
Experiment ID497
Identified moleculemRNA
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Microarray
PubMed ID 23344721   
OrganismHomo sapiens
Experiment descriptionmiR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
AuthorsBolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O.
Journal name Mol Ther Nucleic Acids
Publication year2012
SampleMelanoma cells
Sample namePrimary malignant melanoma cells (0664)
Isolation/purification methods-
Flotation density-
Molecules identified in the studymRNA
Methods used in the studyMicroarray
EV-TRACK -

3
Experiment ID618
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameM14
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

4
Experiment ID619
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameMALME-3M
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

5
Experiment ID621
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameSK-MEL-2
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

6
Experiment ID623
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleMelanoma cells
Sample nameSK-MEL-5
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

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